Titanfall brings players into The Frontier, a place where humans have set up colonies in many solar systems. Two factions are in power here - the IMC (Interstellar Manufacturing Corporation) and the Frontier Militia. The IMC plans to exploit The Frontier of its natural resources to make its shareholders richer while the Frontier Militia controls and defends territories of their own from the IMC. Inevitably, war breaks out and a space corporation named Hammond Robotics starts supplying giant sized Mecha-Combatants called Titans and Spectres to both factions.

In Titanfall, players will choose a faction to fight for and control a human pilot and their selected machine of destruction "Titan", to destroy enemies in an all-out multiplayer fight-fest. Pilots can carry their standard assault weapons, grenades, and an "Anti-Titan Weapon". When inside their Titans, they use much bigger weapons to destroy enemies such as the 40mm Cannon, Plasma Railgun, or Arc Cannon.

With a selection of devastating weapons, a Titan fps concept and five fast-paced multiplayer modes, players must destroy the opposing force or be crushed on the battlefield.