The evil god Set has awakened and Lara must join forces with her rival treasure hunter, Carter Bell, and enslaved Gods, Horus and Isis, to defeat him. The only way to defeat him is to find the lost fragments of Osiris. But Lara must face the elements of nature, creatures of myths and legendary deities.

For the first time, the game features of a 4 player co-op multiplayer experience. Defeat enemies from the Egyptian underworld, avoid horrifying traps and solve mind twisting puzzles to be the ultimate treasure hunter.